A quantitative framework for characterizing the evolutionary history of mammalian gene expression

The evolutionary history of a gene helps predict its function and relationship to phenotypic traits. Although sequence conservation is commonly used to decipher gene function and assess medical relevance, methods for functional inference from comparative expression data are lacking. Here, we use RNA...

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Bibliographic Details
Main Authors: Chen, Jenny (Jennifer), Regev, Aviv
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory 2020
Online Access:https://hdl.handle.net/1721.1/125497