Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide and is strongly associated with chronic Helicobacter pylori (Hp) infection. The ability of Hp to closely adhere to the gastric surface protective mucous layer containing mucins (MUC in humans and Muc in animals), prima...

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Bibliographic Details
Main Authors: Muthupalani, Sureshkumar, Ge, Zhongming, Joy, Joanna, Feng, Yan, Dobey, Carrie, Cho, Hye-Youn, Langenbach, Robert, Wang, Timothy C., Hagen, Susan J., Fox, James G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/125502