Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition

The zinc finger CCCTC-binding protein (CTCF) carries out many functions in the cell. Although previous studies sought to explain CTCF multivalency based on sequence composition of binding sites, few examined how CTCF post-translational modification (PTM) could contribute to function. Here, we perfor...

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Bibliographic Details
Main Authors: Del Rosario, Amanda M, White, Forest M.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2020
Online Access:https://hdl.handle.net/1721.1/125503