Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
© van de Kooij et al. Human NimA-related kinases (Neks) have multiple mitotic and non-mitotic functions, but few substrates are known. We systematically determined the phosphorylation-site motifs for the entire Nek kinase family, except for Nek11. While all Nek kinases strongly select for hydrophobi...
Main Authors: | Van de Kooij, Bert, Creixell Morera, Pau, Van Vlimmeren, Anne Elise, Joughin, Brian Alan, Yaffe, Michael B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2020
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Online Access: | https://hdl.handle.net/1721.1/125507 |
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