Characterization of an A-Site Selective Protein Disulfide Isomerase A1 Inhibitor
Protein disulfide isomerase A1 (PDIA1) is an endoplasmic reticulum (ER)-localized thiol-disulfide oxidoreductase that is an important folding catalyst for secretory pathway proteins. PDIA1 contains two active-site domains (a and a′), each containing a Cys-Gly-His-Cys (CGHC) active-site motif. The tw...
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
American Chemical Society (ACS)
2020
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| Acesso em linha: | https://hdl.handle.net/1721.1/125543 |