A cysteine-based molecular code informs collagen C-propeptide assembly

Fundamental questions regarding collagen biosynthesis, especially with respect to the molecular origins of homotrimeric versus heterotrimeric assembly, remain unanswered. Here, we demonstrate that the presence or absence of a single cysteine in type-I collagen’s C-propeptide domain is a key factor g...

Full description

Bibliographic Details
Main Authors: DiChiara, Andrew Stephen, Li, Rasia C., Suen, Patreece H., Hosseini, Azade S., Taylor, Rebecca J., Weickhardt, Alexander F., Malhotra, Diya, Shoulders, Matthew D.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/125561