A cysteine-based molecular code informs collagen C-propeptide assembly
Fundamental questions regarding collagen biosynthesis, especially with respect to the molecular origins of homotrimeric versus heterotrimeric assembly, remain unanswered. Here, we demonstrate that the presence or absence of a single cysteine in type-I collagen’s C-propeptide domain is a key factor g...
Main Authors: | DiChiara, Andrew Stephen, Li, Rasia C., Suen, Patreece H., Hosseini, Azade S., Taylor, Rebecca J., Weickhardt, Alexander F., Malhotra, Diya, Shoulders, Matthew D. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
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Online Access: | https://hdl.handle.net/1721.1/125561 |
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