XBP1s activation can globally remodel N-glycan structure distribution patterns

XBP1s activation can globally remodel N-glycan structure distribution patterns

Classically, the unfolded protein response (UPR) safeguards secretory pathway proteostasis. The most ancient arm of the UPR, the IRE1-activated spliced X-box binding protein 1 (XBP1s)-mediated response, has roles in secretory pathway maturation beyond resolving proteostatic stress. Understanding the...

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Bibliographic Details
Main Authors: Wong, Madeline Y., Dewal, Mahender, Taylor, Rebecca J., Whittaker, Charles A., Phyo, Pyae, Shoulders, Matthew D., Chen, Kenny,Ph. D.Massachusetts Institute of Technology.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/125565

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https://hdl.handle.net/1721.1/125565

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