QTY code-designed water-soluble Fc-fusion cytokine receptors bind to their respective ligands

Cytokine release syndrome (CRS), or "cytokine storm," is the leading side effect during CAR-T therapy that is potentially life-threatening. It also plays a critical role in viral infections such as COVID-19. Therefore, efficient removal of excessive cytokines is essential for treatment. We...

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Bibliographic Details
Main Authors: Hao, Shilei, Jin, David, Zhang, Shuguang, Qing, Rui
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Published: 2020
Online Access:https://hdl.handle.net/1721.1/125601