A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production

A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production

Collagen overproduction is a feature of fibrosis and cancer, while insufficient deposition of functional collagen molecules and/or the secretion of malformed collagen is common in genetic disorders like osteogenesis imperfecta. Collagen secretion is an appealing therapeutic target in these and other...

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Bibliographic Details
Main Authors: Wong, Madeline Y., Doan, Ngoc Duc, DiChiara, Andrew Stephen, Papa, Louis John, Cheah, Jaime H, Soule, Christian K., Watson, Nicki E., Shoulders, Matthew D.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/125610

Internet

https://hdl.handle.net/1721.1/125610

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