BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension

Background: Deficiencies of iron-sulfur (Fe-S) clusters, metal complexes that control redox state and mitochondrial metabolism, have been linked to pulmonary hypertension (PH), a deadly vascular disease with poorly defined molecular origins. BOLA3 (BolA Family Member 3) regulates Fe-S biogenesis, an...

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Bibliographic Details
Main Authors: Khan, Omar Fizal, Langer, Robert S, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Ovid Technologies (Wolters Kluwer Health) 2020
Online Access:https://hdl.handle.net/1721.1/125622