Retinoic Acid and Germ Cell Development in the Ovary and Testis

Retinoic acid (RA), a derivative of vitamin A, is critical for the production of oocytes and sperm in mammals. These gametes derive from primordial germ cells, which colonize the nascent gonad, and later undertake sexual differentiation to produce oocytes or sperm. During fetal development, germ cel...

Full description

Bibliographic Details
Main Authors: Endo, Tsutomu, Mikedis, Maria M., Nicholls, Peter K., Page, David C, de Rooij, Dirk G.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: MDPI AG 2020
Online Access:https://hdl.handle.net/1721.1/125834