Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration
Microtubule-targeting agents (MTAs) are widely used chemotherapy drugs capable of disrupting microtubule-dependent cellular functions, such as division and migration. We show that two clinically approved MTAs, paclitaxel and vinblastine, each suppress stiffness-sensitive migration and polarization c...
Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Published: |
Cell Press
2020
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Online Access: | https://hdl.handle.net/1721.1/125946 |