Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer

Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer

B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs; however, there are presently no agents that target BCL2A1. The MUC1-C oncoprotein is aberrantly expressed in triple-negative breast ca...

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Bibliographic Details
Main Authors: Hiraki, Masayuki, Maeda, Takahiro, Mehrotra, Neha, Jin, Caining, Alam, Maroof, Bouillez, Audrey, Hata, Tsuyoshi, Tagde, Ashujit, Keating, Amy E., Kharbanda, Surender, Singh, Harpal, Kufe, Donald
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/125967

Internet

https://hdl.handle.net/1721.1/125967

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