Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs; however, there are presently no agents that target BCL2A1. The MUC1-C oncoprotein is aberrantly expressed in triple-negative breast ca...
Main Authors: | Hiraki, Masayuki, Maeda, Takahiro, Mehrotra, Neha, Jin, Caining, Alam, Maroof, Bouillez, Audrey, Hata, Tsuyoshi, Tagde, Ashujit, Keating, Amy E., Kharbanda, Surender, Singh, Harpal, Kufe, Donald |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
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Online Access: | https://hdl.handle.net/1721.1/125967 |
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