Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement
HIV-specific broadly neutralizing antibodies (bNAbs) confer protection after passive immunization, but the immunological mechanisms that drive their development are poorly understood. Structural features of bNAbs indicate that they originate from extensive germinal center (GC) selection, which relie...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2020
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Online Access: | https://hdl.handle.net/1721.1/125968 |