Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence

Cell size varies greatly between cell types, yet within a specific cell type and growth condition, cell size is narrowly distributed. Why maintenance of a cell-type specific cell size is important remains poorly understood. Here we show that growing budding yeast and primary mammalian cells beyond a...

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Bibliographic Details
Main Authors: Neurohr, Gabriel, Terry, Rachel L., Lengefeld, Jette, Bonney, Megan Ellis, Brittingham, Gregory P., Moretto, Fabien, Miettinen, Teemu P, Vaites, Laura Pontano, Soares, Luis M., Paulo, Joao A., Harper, J. Wade, Buratowski, Stephen, Manalis, Scott R, van Werven, Folkert J., Holt, Liam J., Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/125970

Internet

https://hdl.handle.net/1721.1/125970

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