Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses
N-linked glycosylation affects the potency, safety, immunogenicity, and pharmacokinetic clearance of several therapeutic proteins including monoclonal antibodies. A robust control strategy is needed to dial in appropriate glycosylation profile during the course of cell culture processes accurately....
| 主要な著者: | , , , , , , , , , , |
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| その他の著者: | |
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Elsevier BV
2020
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| オンライン･アクセス: | https://hdl.handle.net/1721.1/125974 |