Deciphering eukaryotic gene-regulatory logic with 100 million random promoters
How transcription factors (TFs) interpret cis-regulatory DNA sequence to control gene expression remains unclear, largely because past studies using native and engineered sequences had insufficient scale. Here, we measure the expression output of >100 million synthetic yeast promoter sequences th...
| Main Authors: | , , , , , |
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| 其他作者: | |
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Springer Science and Business Media LLC
2020
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| 在线阅读: | https://hdl.handle.net/1721.1/125982 |