Ni-Catalyzed Cross-Electrophile Coupling for the Synthesis of Skipped Polyenes

Skipped polyenes featuring high (E)-selectivity and varying methyl substitution patterns are synthesized using a nickel-catalyzed cross-coupling reaction between allyl trifluoroacetates and vinyl bromides. The utility of this cross-electrophile coupling is showcased in part by the synthesis of the R...

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Bibliographic Details
Main Authors: McGeough, Catherine P., Strom, Alexandra E., Jamison, Timothy F
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/125989