Global analyses of the dynamics of mammalian microRNA metabolism

Rates of production and degradation together specify microRNA (miRNA) abundance and dynamics. Here, we used approach-to-steady-state metabolic labeling to assess these rates for 176 miRNAs in contact-inhibited mouse embryonic fibroblasts (MEFs), 182 miRNAs in dividing MEFs, and 127 miRNAs in mouse e...

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Bibliographic Details
Main Authors: Kingston, Elena, Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory 2020
Online Access:https://hdl.handle.net/1721.1/126013