Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes

Synapses contain hundreds of distinct proteins whose heterogeneous expression levels are determinants of synaptic plasticity and signal transmission relevant to a range of diseases. Here, we use diffusible nucleic acid imaging probes to profile neuronal synapses using multiplexed confocal and super-...

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Bibliographic Details
Main Authors: Guo, Syuan-Ming, Veneziano, Remi, Gordonov, Simon, Li, Li, Danielson, Eric W, Perez de Arce, Karen, Park, Demian, Kulesa, Anthony Benjamin, Wamhoff, Eike-Christian, Blainey, Paul C., Blainey, Paul C, Boyden, Edward, Cottrell, Jeffrey R., Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/126016