Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix
Extracellular matrix (ECM) deposition is a hallmark of many diseases, including cancer and fibroses. To exploit the ECM as an imaging and therapeutic target, we developed alpaca-derived libraries of “nanobodies” against disease-associated ECM proteins. We describe here one such nanobody, NJB2, speci...
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences
2020
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| Online Access: | https://hdl.handle.net/1721.1/126031 |