Cytoskeletal tension actively sustains the migratory T‐cell synaptic contact

When migratory T cells encounter antigen-presenting cells (APCs), they arrest and form radially symmetric, stable intercellular junctions termed immunological synapses which facilitate exchange of crucial biochemical information and are critical for T-cell immunity. While the cellular processes unde...

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Bibliographic Details
Main Authors: Kumari, Sudha, Mak, Michael, Poh, Yeh Chuin, Tohme, Mira, Watson, Nicki, Melo, Mariane Bandeira, Janssen, Erin, Dustin, Michael, Geha, Raif, Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: EMBO 2020
Online Access:https://hdl.handle.net/1721.1/126042