Bacterial encapsulins as orthogonal compartments for mammalian cell engineering

Bacterial encapsulins as orthogonal compartments for mammalian cell engineering

We genetically controlled compartmentalization in eukaryotic cells by heterologous expression of bacterial encapsulin shell and cargo proteins to engineer enclosed enzymatic reactions and size-constrained metal biomineralization. The shell protein (EncA) from Myxococcus xanthus auto-assembles into n...

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Bibliographic Details
Main Authors: Massner, Christoph, Erdmann, Philipp, Stelzl, Anja, Rolbieski, Hannes, Desai, Mitul, Bricault, Sarah Jean, Wörner, Tobias P., Snijder, Joost, Geerlof, Arie, Fuchs, Helmut, de Angelis, Martin Hrabĕ, Heck, Albert J.R., Jasanoff, Alan Pradip, Ntziachristos, Vasilis, Plitzko, Jürgen, Westmeyer, Gil G., Fritz, Sigmund
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/126054

Internet

https://hdl.handle.net/1721.1/126054

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