Postdiagnosis Loss of Skeletal Muscle, but Not Adipose Tissue, Is Associated with Shorter Survival of Patients with Advanced Pancreatic Cancer

Background: Pancreatic cancer is associated with development of cachexia, a wasting syndrome thought to limit survival. Few studies have longitudinally quantified peripheral tissues or identified biomarkers predictive of future tissue wasting. Methods: Adipose and muscle tissue were measured by comp...

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Bibliographic Details
Main Authors: Babic, Ana, Rosenthal, Michael H., Bamlet, William R., Takahashi, Naoki, Sugimoto, Motokazu, Danai, Laura V., Morales-Oyarvide, Vicente, Khalaf, Natalia, Dunne, Richard F., Brais, Lauren K., Welch, Marisa W., Zellers, Caitlin L., Dennis, Courtney, Rifai, Nader, Prado, Carla M., Caan, Bette, Sundaresan, Tilak K., Meyerhardt, Jeffrey A., Kulke, Matthew H., Clish, Clary B., Ng, Kimmie, Vander Heiden, Matthew G., Petersen, Gloria M., Wolpin, Brian M.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Association for Cancer Research (AACR) 2020
Online Access:https://hdl.handle.net/1721.1/126075