CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes

CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes

A CuH-catalyzed enantioselective hydroamidation reaction of vinylarenes has been developed using readily accessible 1,4,2-dioxazol-5-ones as electrophilic amidating reagents. This method provides a straightforward and efficient approach to synthesize chiral amides in good yields with high levels of...

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Bibliographic Details
Main Authors: Zhou, Yujing, Engl, Oliver D., Bandar, Jeffrey, Chant, Emma D., Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Wiley 2020
Online Access:https://hdl.handle.net/1721.1/126087

Internet

https://hdl.handle.net/1721.1/126087

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