Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

The Mad1-Mad2 heterodimer is the catalytic hub of the spindle assembly checkpoint (SAC), which controls M phase progression through a multi-subunit anaphase inhibitor, the mitotic checkpoint complex (MCC) [1, 2]. During interphase, Mad1-Mad2 generates MCC at nuclear pores [3]. After nuclear envelope...

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Bibliographic Details
Main Authors: Rodriguez-Rodriguez, Jose-Antonio, Lewis, Clare, McKinley, Kara Lavidge, Sikirzhytski, Vitali, Corona, Jennifer, Maciejowski, John, Khodjakov, Alexey, Cheeseman, Iain M, Jallepalli, Prasad V.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126113

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https://hdl.handle.net/1721.1/126113

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