Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon

Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon

Background: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in mitochondria for most animal cells. Mutations in POLG are the most common single-gene c...

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Bibliographic Details
Main Authors: Khan, Yousuf A, Jungreis, Irwin, Wright, James C, Mudge, Jonathan M, Choudhary, Jyoti S, Firth, Andrew E, Kellis, Manolis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central 2020
Online Access:https://hdl.handle.net/1721.1/126141

Internet

https://hdl.handle.net/1721.1/126141

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