A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria
Antibiotic screens typically rely on growth inhibition to characterize compound bioactivity—an approach that cannot be used to assess the bactericidal activity of antibiotics against bacteria in drug-tolerant states. To address this limitation, we developed a multiplexed assay that uses metabolism-s...
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Bibliographic Details
| Main Authors: |
Stokes, Jonathan,
Gutierrez, Arnaud,
Lopatkin, Allison J.,
Andrews, Ian W.,
French, Shawn,
Matic, Ivan,
Brown, Eric D.,
Collins, James J. |
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| Other Authors: |
Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
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| Format: | Article
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| Language: | English |
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| Published: |
Springer Science and Business Media LLC
2020
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| Online Access: | https://hdl.handle.net/1721.1/126163
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