A platform for multiplexed colorimetric microRNA detection using shape-encoded hydrogel particles

We report a platform utilizing a reporter enzyme, which produces a chromogenic indigo precipitate that preferentially localizes within a hydrogel microparticle. The 3D network of the hydrogel maintains the rapid target binding kinetics found in solution, while multiplexed target detection is achieve...

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Bibliographic Details
Main Authors: Juthani, Nidhi, Doyle, Patrick S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC) 2020
Online Access:https://hdl.handle.net/1721.1/126187