Pro-organic radical contrast agents (“pro-ORCAs”) for real-time MRI of pro-drug activation in biological systems

Nitroxide-based organic-radical contrast agents (ORCAs) are promising as safe next-generation magnetic resonance imaging (MRI) tools. Nevertheless, stimuli-responsive ORCAs that enable MRI monitoring of prodrug activation have not been reported; such systems could open new avenues for prodrug valida...

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Bibliographic Details
Main Authors:	Nguyen, Hung VanThanh, Detappe, Alexandre, Harvey, Peter, Gallagher, Nolan, Mathieu, Clelia, Agius, Michael P., Zavidij, Oksana, Wang, Wencong, Jiang, Yivan, Rajca, Andrzej, Jasanoff, Alan Pradip, Ghobrial, Irene M., Ghoroghchian, Paiman Peter, Johnson, Jeremiah A.
Other Authors:	Massachusetts Institute of Technology. Department of Chemistry
Format:	Article
Published:	Royal Society of Chemistry (RSC) 2020
Online Access:	https://hdl.handle.net/1721.1/126188

Internet

https://hdl.handle.net/1721.1/126188

Pro-organic radical contrast agents (“pro-ORCAs”) for real-time MRI of pro-drug activation in biological systems

Internet

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