Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer

Background: Invasive lobular carcinoma (ILC) as a disease entity distinct from invasive ductal carcinoma (IDC) has merited focused studies of the genomic landscape, but those to date are largely limited to the assessment of early-stage cancers. Given that genomic alterations develop as acquired resi...

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Bibliographic Details
Main Authors: Feng, Y, Jen, D. X.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Oxford University Press (OUP) 2020
Online Access:https://hdl.handle.net/1721.1/126195