Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders

Many craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such as transcription or ribosome biogenesis. Although it is understood that many of these malformations are a consequence of defects in cranial neural crest cells, a cell type t...

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Bibliographic Details
Main Authors: Calo, Eliezer, Gu, Bo, Bowen, Margot E., Aryan, Fardin, Zalc, Antoine, Liang, Jialiang, Flynn, Ryan A., Swigut, Tomek, Chang, Howard Y., Attardi, Laura D., Wysocka, Joanna
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/126251