Memory engrams: Recalling the past and imagining the future

In 1904, Richard Semon introduced the term “engram” to describe the neural substrate for storing memories. An experience, Semon proposed, activates a subset of cells that undergo off-line, persistent chemical and/or physical changes to become an engram. Subsequent reactivation of this engram induces...

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Bibliographic Details
Main Authors: Josselyn, Sheena A., Tonegawa, Susumu
Other Authors: RIKEN-MIT Center for Neural Circuit Genetics
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020
Online Access:https://hdl.handle.net/1721.1/126261