Deploying Fluorescent Nucleoside Analogues for High‐Throughput Inhibitor Screening

High-throughput small-molecule screening in drug discovery processes commonly rely on fluorescence-based methods including fluorescent polarization and fluorescence/Förster resonance energy transfer. These techniques use highly accessible instrumentation; however, they can suffer from high false-neg...

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Bibliographic Details
Main Authors: Seebald, Leah, Madec, Amael, Imperiali, Barbara
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Wiley 2020
Online Access:https://hdl.handle.net/1721.1/126269