Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach

Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach

Background & Aims: Loss of claudin 18 (CLDN18), a membrane-spanning tight junction protein, occurs during early stages of development of gastric cancer and associates with shorter survival times of patients. We investigated whether loss of CLDN18 occurs in mice that develop intraepithelial neopl...

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Bibliographic Details
Main Authors: Hagen, Susan J., Ang, Lay-Hong, Zheng, Yi, Karahan, Salih N., Wu, Jessica, Wang, Yaoyu E., Caron, Tyler, Gad, Aniket P., Muthupalani, Sureshkumar, Fox, James G
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126290

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https://hdl.handle.net/1721.1/126290

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