Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings

Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings

Background: Innovations in drug eluting stent designs make it increasingly important to develop models for differentiating performance through spatial definition of drug, receptor binding and cell state. Methods: Two designs of sirolimus analog eluting stents were implanted into porcine coronary art...

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Bibliographic Details
Main Authors: Tzafriri, Abraham R., Garcia-Polite, Fernando, Li, Xiaojian, Keating, John, Balaguer, Josep-Maria, Zani, Brett, Bailey, Lynn, Markham, Peter, Kiorpes, Timothy C., Carlyle, Wenda, Edelman, Elazer R
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126297

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https://hdl.handle.net/1721.1/126297

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