Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes

Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes

Huntington’s disease (HD) is an incurable neurodegenerative disorder caused by CAG trinucleotide expansions in the huntingtin gene. Markers of both systemic and CNS immune activation and inflammation have been widely noted in HD and mouse models of HD. In particular, elevation of the pro-inflammator...

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Bibliographic Details
Main Authors: Wertz, Mary H., Pineda, S. Sebastian, Lee, Hyeseung, Kulicke, Ruth, Kellis, Manolis, Heiman, Myriam
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: BioMed Central 2020
Online Access:https://hdl.handle.net/1721.1/126311

Internet

https://hdl.handle.net/1721.1/126311

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