Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies
Eukaryotic genes are regulated by multivalent transcription factor complexes. Through cooperative self-assembly, these complexes perform nonlinear regulatory operations involved in cellular decision-making and signal processing. In this study, we apply this design principle to synthetic networks, te...
Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2020
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Online Access: | https://hdl.handle.net/1721.1/126317 |