A pathway for mitotic chromosome formation

A pathway for mitotic chromosome formation

Mitotic chromosomes fold as compact arrays of chromatin loops.To identify the pathway of mitotic chromosome formation, we combined imaging and Hi-C analysis of synchronous DT40 cell cultures with polymer simulations. Here we show that in prophase, the interphase organization is rapidly lost in a con...

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Bibliographic Details
Main Authors: Gibcus, Johan H., Samejima, Kumiko, Goloborodko, Anton, Samejima, Itaru, Naumova, Natalia, Nubler, Johannes, Kanemaki, Masato T., Xie, Linfeng, Paulson, James R., Earnshaw, William C., Mirny, Leonid A, Dekker, Job
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020
Online Access:https://hdl.handle.net/1721.1/126370

Internet

https://hdl.handle.net/1721.1/126370

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