Dexmedetomidine promotes biomimetic non-rapid eye movement stage 3 sleep in humans: A pilot study

Objectives Sleep, which comprises of rapid eye movement (REM) and non-REM stages 1–3 (N1–N3), is a natural occurring state of decreased arousal that is crucial for normal cardiovascular, immune and cognitive function. The principal sedative drugs produce electroencephalogram beta oscillations, which...

Full description

Bibliographic Details
Main Authors: Akeju, Oluwaseun, Hobbs, Lauren E., Gao, Lei, Burns, Sara M., Pavone, Kara J., Plummer, George S., Walsh, Elisa C., Houle, Tim T., Kim, Seong-Eun, Bianchi, Matt T., Ellenbogen, Jeffrey M., Brown, Emery Neal
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126436