A comparison of nanoparticle-antibody conjugation strategies in sandwich immunoassays

A comparison of nanoparticle-antibody conjugation strategies in sandwich immunoassays

Point-of-care (POC) diagnostics such as lateral flow and dipstick immunoassays use gold nanoparticle (NP)-antibody conjugates for visual readout. We investigated the effects of NP conjugation, surface chemistries, and antibody immobilization methods on dipstick performance. We compared orientational...

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Bibliographic Details
Main Authors: Tam, Justina O., de Puig Guixe, Helena, Yen, Chun-wan, Bosch, Irene, Gomez-Marquez, Jose Zacapa, Clavet, Charles, Hamad-Schifferli, Kimberly, Gehrke, Lee
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Informa UK Limited 2020
Online Access:https://hdl.handle.net/1721.1/126437

Internet

https://hdl.handle.net/1721.1/126437

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