Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors

Background: The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell's specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a repertoire of millions of unique receptors in e...

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Bibliographic Details
Main Authors: Chu, Nathaniel David, Birnbaum, Michael E, Alm, Eric J, Bi, Haixin S
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/126457