Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids

Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids

Although the association between the microbiome and IBD and liver diseases is known, the cause and effect remain elusive. By connecting human microphysiological systems of the gut, liver, and circulating Treg and Th17 cells, we created a multi-organ model of ulcerative colitis (UC) ex vivo. The appr...

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Bibliographic Details
Main Authors: Trapecar, Martin, Communal, Catherine, Velazquez, Jason G, Maass, Christian Alexander, Huang, Yu-Ja, Schneider, Kirsten, Wright, Charles, Butty, Vincent L G, Eng, George M., Yilmaz, Omer, Trumper, David L, Griffith, Linda G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126464

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https://hdl.handle.net/1721.1/126464

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