R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice

R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice

Human chromosome 16p11.2 microdeletion is among the most common gene copy number variations (CNVs) known to confer risk for intellectual disability (ID) and autism spectrum disorder (ASD) and affects an estimated 3 in 10 000 people. Caused by a single copy deletion of ∼27 genes, 16p11.2 microdeletio...

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Bibliographic Details
Main Authors: Stoppel, Laura Jane, Kazdoba, Tatiana M, Schaffler, Melanie D, Preza, Anthony R., Heynen, Arnold J, Crawley, Jacqueline N, Bear, Mark
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/126513

Internet

https://hdl.handle.net/1721.1/126513

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