Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of in vivo binding of RNA-binding proteins is greatly facilitated by the enhanced crosslinking and immunoprecipitati...

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Bibliographic Details
Main Authors: Yang, Ei-Wen, Bahn, Jae Hoon, Yun-Hua Hsiao, Esther, Tan, Boon Xin, Sun, Yiwei, Fu, Ting, Zhou, Bo, Van Nostrand, Eric L., Pratt, Gabriel A., Freese, Peter Dale, Wei, Xintao, Quinones-Valdez, Giovanni, Urban, Alexander E., Graveley, Brenton R., Burge, Christopher B, Yeo, Gene W., Xiao, Xinshu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Nature 2020
Online Access:https://hdl.handle.net/1721.1/126514

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https://hdl.handle.net/1721.1/126514

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