Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of in vivo binding of RNA-binding proteins is greatly facilitated by the enhanced crosslinking and immunoprecipitati...

Podrobná bibliografie
Hlavní autoři:	Yang, Ei-Wen, Bahn, Jae Hoon, Yun-Hua Hsiao, Esther, Tan, Boon Xin, Sun, Yiwei, Fu, Ting, Zhou, Bo, Van Nostrand, Eric L., Pratt, Gabriel A., Freese, Peter Dale, Wei, Xintao, Quinones-Valdez, Giovanni, Urban, Alexander E., Graveley, Brenton R., Burge, Christopher B, Yeo, Gene W., Xiao, Xinshu
Další autoři:	Massachusetts Institute of Technology. Department of Biology
Médium:	Článek
Jazyk:	English
Vydáno:	Springer Nature 2020
On-line přístup:	https://hdl.handle.net/1721.1/126514

Podobné jednotky

Sequence, Structure, and Context Preferences of Human RNA Binding Proteins
Autor: Freese, Peter, a další
Vydáno: (2018)

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
Autor: Xiao, Rui, a další
Vydáno: (2020)

Biochemical and functional characterization of human RNA binding proteins
Autor: Freese, Peter (Peter Dale)
Vydáno: (2018)

RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins
Autor: Benoit Bouvrette, Louis Philip, a další
Vydáno: (2022)

A large-scale binding and functional map of human RNA-binding proteins
Autor: Freese, Peter Dale, a další
Vydáno: (2021)

RNA Bind-n-Seq: Quantitative Assessment of the Sequence and Structural Binding Specificity of RNA Binding Proteins
Autor: Lambert, Nicole, a další
Vydáno: (2017)

RNA aptamers binding the double-stranded RNA-binding domain.
Autor: Hallegger, M, a další
Vydáno: (2006)

An in vitro technique to identify the RNA binding-site sequences for RNA-binding proteins
Autor: SunKyung Choi, a další
Vydáno: (2017-07-01)

Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP
Autor: Zhuoyi Song, a další
Vydáno: (2025-02-01)

Allele-specific binding (ASB) analyzer for annotation of allele-specific binding SNPs
Autor: Ying Li, a další
Vydáno: (2023-12-01)

Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing
Autor: Gupta, Kavi, a další
Vydáno: (2024)

Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing
Autor: Kavi Gupta, a další
Vydáno: (2024-01-01)

Identification of RNA-binding Proteins
Autor: Kazuya Masuda, a další
Vydáno: (2016-09-01)

RNA-Binding Proteins in Cardiomyopathies
Autor: De-Li Shi
Vydáno: (2024-03-01)

RBDmap: a proteome-wide repertoire of RNA-binding domains of human RNA-binding proteins
Autor: Palomares, A, a další
Vydáno: (2017)

Understanding regulation of mRNA by RNA binding proteins
Autor: Robertson, Alexander De Jong
Vydáno: (2014)

Impact of MICA 3′UTR allelic variability on miRNA binding prediction, a bioinformatic approach
Autor: Karen Toledo-Stuardo, a další
Vydáno: (2023-12-01)

Chaperone-assisted multiphase condensation of RNA-binding-deficient TDP-43
Autor: Yeo, Kian Hua
Vydáno: (2024)

RNA-binding proteins in bone pathophysiology
Autor: Paola Maroni, a další
Vydáno: (2024-06-01)

Editorial: RNA binding proteins in neuroscience
Autor: Anca F. Savulescu, a další
Vydáno: (2023-12-01)

Regulatory role of RNA-binding proteins in microRNA biogenesis
Autor: Claire Hynes, a další
Vydáno: (2024-03-01)

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap
Autor: Castello, A, a další
Vydáno: (2017)

Phenylpyrazoles as Inhibitors of the m6A RNA-Binding Protein YTHDF2
Autor: Xiaqiu Qiu, a další
Vydáno: (2025-02-01)

Differential conformational dynamics in two type-A RNA-binding domains drive the double-stranded RNA recognition and binding
Autor: Firdousi Parvez, a další
Vydáno: (2024-08-01)

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery
Autor: Endo, Kei, a další
Vydáno: (2017)

Detection of RNA-binding Proteins by RNA Pull-down in Adipocyte Culture
Autor: Bai, Qianfan, a další
Vydáno: (2017)

Dynamic expression of RNA-binding proteins in spermatogenesis based on RNA-seq
Autor: LI Kai, MANG Xin-yu, ZOU Ding-feng, LI Meng-zhen, MIAO Shi-ying, WANG Lin-fang, SONG Wei
Vydáno: (2021-06-01)

Engineering double-stranded RNA binding activity into the Drosha double-stranded RNA binding domain results in a loss of microRNA processing function.
Autor: Joshua C Kranick, a další
Vydáno: (2017-01-01)

Quantifying negative selection in human 3ʹ UTRs uncovers constrained targets of RNA-binding proteins
Autor: Scott D. Findlay, a další
Vydáno: (2024-01-01)

Post-transcriptional coordination by an RNA-binding protein
Autor: Wolf, Joshua Jaeger
Vydáno: (2010)

Towards understanding of PRC2 binding to RNA
Autor: Yan, Junli, a další
Vydáno: (2021)

RNA-binding proteins as versatile metabolic regulators
Autor: Ellie Koletsou, a další
Vydáno: (2025-01-01)

RNA Binding Properties of SOX Family Members
Autor: Seyed Mohammad Ghafoori, a další
Vydáno: (2024-07-01)

Role of Optimization in RNA–Protein-Binding Prediction
Autor: Shrooq Alsenan, a další
Vydáno: (2024-02-01)

Functions of RNA-Binding Proteins in Cardiovascular Disease
Autor: Grégoire Ruffenach, a další
Vydáno: (2023-12-01)

Benchmarking and building DNA binding affinity models using allele-specific and allele-agnostic transcription factor binding data
Autor: Xiaoting Li, a další
Vydáno: (2024-10-01)

The dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome
Autor: Washburn, Michael C., a další
Vydáno: (2014)

Characterizing RNA-binding ligands on structures, chemical information, binding affinity and drug-likeness
Autor: Cong Fan, a další
Vydáno: (2023-12-01)

RNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
Autor: Yoona Seo, a další
Vydáno: (2024-05-01)

RNA-binding Protein Immunoprecipitation (RIP) to Examine AUF1 Binding to Senescence-Associated Secretory Phenotype (SASP) Factor mRNA
Autor: Elise Alspach, a další
Vydáno: (2015-05-01)