Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

CRISPR (clustered regularly interspaced short palindromic repeats) genome-editing experiments offer enormous potential for the evaluation of genomic loci using arrayed single guide RNAs (sgRNAs) or pooled sgRNA libraries. Numerous computational tools are available to help design sgRNAs with optimal...

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Bibliographic Details
Main Authors: Zhang, Feng, Pinello, Luca
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: Springer Nature 2020
Online Access:https://hdl.handle.net/1721.1/126595

Internet

https://hdl.handle.net/1721.1/126595

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