Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

Signaling abnormalities in immune responses in the small intestine can trigger chronic type 2 inflammation involving interaction of multiple immune cell types. To systematically characterize this response, we analyzed 58,067 immune cells from the mouse small intestine by single-cell RNA sequencing (...

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Bibliographic Details
Main Authors: Xu, Heping, Ding, Jiarui, Porter, Caroline, Wallrapp, Antonia, Tabaka, Marcin, Ma, Sai, Fu, Shujie, Guo, Xuanxuan, Riesenfeld, Samantha J., Su, Chienwen, Dionne, Danielle, Nguyen, Lan T., Lefkovith, Ariel, Ashenberg, Orr, Burkett, Patrick R., Shi, Hai Ning, Rozenblatt-Rosen, Orit, Graham, Daniel B., Kuchroo, Vijay K., Regev, Aviv, Xavier, Ramnik J.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126748

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https://hdl.handle.net/1721.1/126748

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